WebSome medications for epilepsy can increase your risk of osteoporosis and broken bones. The exact reason for this is not entirely understood. But it's thought that some anti … Web8. mar 2024 · Phenobarbital side effects. Phenobarbital may cause a severe allergic reaction. Stop taking phenobarbital and get emergency medical help if you have signs of …
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WebThe CYP450 enzyme-inducing AEDs such as phenytoin, phenobarbital, carbamazepine, and primidone are the most common AEDs associated with bone disorders while the data regarding the effect of valproate and newer AEDs such as lamotrigine, gabapentin, vigabatrin, levetiracetam, and topiramate on bone metabolism and bone density are … WebOsteoporosis is a bone disease that occurs when the body loses too much bone, makes too little bone, or both. As a result, bones become weak and may break from a fall or, in serious cases, from sneezing or minor bumps. Osteoporosis means “porous bone.” Viewed under a microscope, healthy bone looks like a honeycomb. Web6. sep 2006 · AEDs have been identified as an independent risk factor for low bone density and osteoporosis . ... (odds ratio 1.14–1.79) and a dose response relationship was reported with carbamazepine (CBZ), phenobarbital (PB), oxcarbazepine (OXC), clonazepam (CZP) and valproate (VPA). Fracture risk was higher for hepatic enzyme inducing AEDs such as ... sanitary wear definition