WebFunction [ edit] The CtBP1 protein was originally identified as a human protein that bound a PLDLS motif in the C-terminus of adenovirus E1A proteins. It and the related protein CTBP2 were later shown to function as transcriptional corepressors. [7] That is, regulatory proteins that bind to sequence-specific DNA-binding proteins and help turn ... Web(B) CtBP1 is SUMOylated in vitro in the presence of PIAS1. Anti-CtBP1 Western blotting was used to detect free CtBP1 and CtBP1-SUMO conjugates. (C) Both PIAS1 and PIASx promote CtBP1 SUMOylation in vitro. (D) Endogenous CtBP1 is SUMOylated. Immunoprecipitates (IP) from HeLa cells, untransfected (lanes 1 and 2) or transfected …
CtBP Antibody (E-12) SCBT - Santa Cruz Biotechnology
WebThis product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility. - Improved sensitivity and specificity. - Long-term security of supply. - Animal-free production. For more information see here. Our RabMAb ® technology is a patented hybridoma-based technology ... WebMar 23, 2024 · The CTBP1 gene encodes a transcriptional regulator that interacts with chromatin-modifying enzymes to modulate gene expression in multiple cellular pathways. CTBP1 is thought to function mainly in transcriptional repression through recruitment of … ipower imap setup
Exome sequencing identified a de novo frameshift pathogenic
WebThe interaction occurs via the CtBP1 interaction consensus motif PVPLS within the PDZ-like domain of SATB1. The acetylation of SATB1 upon LiCl and ionomycin treatments disrupts its association with CtBP1, resulting in enhanced target gene expression. Chromatin immunoprecipitation analysis indicated that the occupancy of CtBP1 and HDAC1 is ... WebMay 10, 2024 · Objectives LncRNA CTBP1-AS2 has been reported to be involved in type 2 diabetes and cardiomyocyte hypertrophy, while its roles in other human diseases are unknown. Our preliminary deep sequencing analysis showed altered expression of CTBP1-AS2 in osteoarthritis (OA). In addition, CTBP1-AS2 was inversely correlated with miR … WebJan 15, 2024 · CtBP Antibody (E-12) is an IgG 1 κ mouse monoclonal CtBP antibody (also designated CTBP1/2 antibody) suitable for the detection of the CtBP protein of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA. CtBP Antibody (E-12) is available as both the non-conjugated anti-CtBP antibody form, as well as multiple conjugated forms of … ipower inc. irwindale ca